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Damage to Brain’s Right Uncinate Fasciculus Linked to Post-Injury Criminal Behavior

Researchers found that disrupting this white matter tract can undermine moral regulation, pointing to new criteria for evaluating legal responsibility.

Overview

  • Published in Molecular Psychiatry, the researchers compared brain scans from 17 individuals who began criminal behavior after brain injuries with 706 control patients exhibiting other neurological issues.
  • Injuries to the right uncinate fasciculus were the most consistent finding among those with new onset criminal or violent acts.
  • The right uncinate fasciculus connects brain regions responsible for emotion processing with areas that guide decision-making.
  • Connectome analysis reinforced that disrupting this tract may impair impulse control, empathy and moral judgment.
  • The findings could help clinicians identify at-risk patients early and encourage courts to factor brain damage into assessments of criminal responsibility.