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Cystic Fibrosis Advances Lift Survival as Argentina Details Access Gains and Ongoing Gaps

Specialists credit CFTR modulators for measurable increases in life expectancy highlighted at the ECFS Congress.

Overview

  • Experts at the ECFS meeting in Milan reported longer survival linked to CFTR modulators and warned that high prices still limit access to innovative drugs worldwide.
  • Argentina’s national registry counted 1,888 people with cystic fibrosis through March 2025, a prevalence of roughly 1 in 6,700 births, with 80.2% younger than 26.
  • A 21-year review from HIGA R. Rossi in La Plata found overall survival of 82% at five years, 72% at ten years, and 40% at twenty years among 124 adults.
  • Dr. Ezequiel Baran said Gador’s locally produced triple therapy has demonstrated bioequivalence to the original drug with the same effectiveness, positioning it as a broader access option in Argentina.
  • A three-center survey documented five recent pregnancies carried to term by women who remained on triple therapy without complications and with clinical stability.