Overview
- Both programs enter 9-3, meeting for the first time at Camping World Stadium in Orlando.
- USF's Byrum Brown and ODU's Colton Joseph opted out, with Gaston Moore and Quinn Henicle set to start under center.
- Pre-game odds slightly favor South Florida by roughly 2.5 to 4 points, with totals near 52 to 53.
- The matchup offers Old Dominion a chance at a 10th win and just its second bowl victory in program history.
- The Cure Bowl maintains its charitable focus, having raised more than $6 million for cancer research since 2015.