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CU Boulder Engineers Advance Electrowetting OCT Prototype for Compact Clinical Imaging

Researchers plan to miniaturize the scanner into flexible endoscopes to validate its performance in human tissues.

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Overview

  • The prototype uses electrowetting-based beam steering instead of mechanical mirrors to cut power consumption and reduce moving parts.
  • Laboratory tests on zebrafish eyes met the team’s resolution targets of about 10 microns axially and 5 microns laterally and clearly resolved cornea and iris structures.
  • The findings were published in Optics Express and backed by funding from the Office of Naval Research, the National Institutes of Health and the National Science Foundation.
  • Researchers aim to miniaturize the scanner into flexible, small-diameter endoscopes for potential retinal and coronary imaging applications.
  • Additional engineering work and validation in human-relevant tissues are needed before the device can be integrated into clinical diagnostic workflows.