CRISPR/Cas9 Editing Enables Euglena to Produce Biofuel-Compatible Wax Esters

Researchers at Osaka Metropolitan University have genetically modified Euglena gracilis to create wax esters with improved cold flow properties for biofuel applications.

Using CRISPR/Cas9, scientists edited the genome of Euglena gracilis to produce wax esters with shorter carbon chains.
The modified wax esters exhibit better cold flow properties, making them more suitable as biofuel feedstock.
This breakthrough addresses the issue of solidification in colder temperatures seen with biofuels derived from animal fats.
Euglena gracilis is advantageous as a biofuel source due to its ability to grow through photosynthesis and anaerobic conditions.
The technology is expected to replace some petroleum-based wax ester production with biological sources, enhancing sustainability.