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CRISPR-Edited Fungus Boosts Mycoprotein Efficiency, Cuts Modeled Emissions

Researchers deleted two native genes to boost efficiency without adding foreign DNA.

Overview

  • Published November 19 in Trends in Biotechnology, the Jiangnan University study reports a gene-edited Fusarium strain named FCPD.
  • Lab tests showed FCPD used 44% less sugar to yield the same protein and produced protein 88% faster than the original strain.
  • Life-cycle modeling across six countries found up to about 60% lower greenhouse gas emissions versus conventional Fusarium production.
  • Compared with chicken production in China, the mycoprotein required roughly 70% less land and reduced freshwater pollution risk by about 78%.
  • Edits removed chitin synthase to thin cell walls and pyruvate decarboxylase to adjust metabolism, improving digestibility and lowering nutrient inputs, with scale-up and regulatory pathways still ahead.