Overview

• Left tackle Tyler Guyton remains in the concussion protocol and will miss Sunday, joining Cooper Beebe (foot) and Tyler Booker (high ankle sprain) on the sideline.
• Pro Bowl left guard Tyler Smith is questionable after not practicing all week, raising the possibility of a fourth missing starter on the offensive line.
• Nate Thomas will make his first career start at left tackle, with Brock Hoffman starting at center and T.J. Bass available inside after filling in last week.
• Top receiver CeeDee Lamb and returner KaVontae Turpin are out, while safety Malik Hooker is sidelined with a toe injury and Juanyeh Thomas will replace him.
• Running back Miles Sanders is questionable, rookie Jaydon Blue is likely to be active for returns and carries, and cornerbacks DaRon Bland and Trevon Diggs will play.