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Cowboys Host Cardinals on Monday Night Football With Brissett Starting, Dallas a Slight Favorite

Kyler Murray remains out with a foot injury, positioning Jacoby Brissett to lead Arizona in a matchup projected to be high scoring with a narrow edge to Dallas.

Jacoby Brissett #7 of the Arizona Cardinals looks to pass in the second quarter of a game against the Green Bay Packers at State Farm Stadium on October 19, 2025 in Glendale, Arizona.
Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images
Ron Chenoy-Imagn Images
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Overview

  • Kickoff is 8:15 p.m. ET at AT&T Stadium on ESPN and ABC, with an alternate Manningcast on ESPN2 and streaming options that include Fubo.
  • Sportsbooks list Dallas at roughly -3 to -3.5 with a total near 53.5 points heading into the primetime game.
  • Arizona coach Jonathan Gannon confirmed Brissett will make his third straight start, while Murray is not starting and remains listed with a foot injury.
  • Model-driven forecasts give the Cowboys a modest advantage — Dimers projects a 61% win probability and a close score around 28-25.
  • Dallas enters with one of the NFL’s top passing attacks and one of its leakiest defenses, and Arizona has dropped five straight one-score games despite efficient play from Brissett and TE Trey McBride.