Overview
- Kickoff is 8:15 p.m. ET at AT&T Stadium on ESPN/ABC, with a ManningCast on ESPN2 and streaming on the ESPN app and Fubo.
 - Arizona coach Jonathan Gannon confirmed Jacoby Brissett as the starter with Kyler Murray limited and potentially active as a backup.
 - Sportsbooks list Dallas around -3 to -3.5 with a total near 53.5, and moneylines roughly Cowboys -168 and Cardinals +145 at publication.
 - Models and panels tilt toward Dallas, including a Dimers simulation showing a 61% win probability for the Cowboys, though several picks see a tight game and potential Cardinals cover.
 - Dallas pairs a top-tier offense with one of the league’s leakiest defenses, while Arizona rides a five-game skid marked by one-score losses and recent series success against the Cowboys.