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COVID-19 Vaccination Reduces Dialysis Need and Death in Acute Kidney Injury Patients

The study highlights vaccination’s ability to curb severe kidney damage, boosting survival among hospitalized COVID-19 patients.

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A person receives a Covid-19 vaccine in Valencia, Spain in 2023.
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Overview

  • Among 972 patients who developed acute kidney injury during hospitalization, vaccinated individuals were less likely to remain on dialysis after discharge and showed higher survival rates than unvaccinated patients.
  • Unvaccinated patients had 2.56 times the odds of requiring post-discharge continuous renal replacement therapy, 5.54 times the risk of dying in hospital and 4.78 times the risk of long-term mortality compared with vaccinated patients.
  • Researchers retrospectively analyzed electronic records of about 3,500 adults admitted with COVID-19 between March 2020 and March 2022, with 467 vaccinated and 411 unvaccinated developing AKI.
  • Study authors noted limitations including missing baseline creatinine levels, lack of data on COVID-19 severity and no evaluation of booster dose effects.
  • Health and Human Services Secretary Robert F. Kennedy Jr. recently removed routine COVID-19 vaccinations for healthy children and pregnant women from the CDC’s immunization schedule, sparking discussion over evolving guidelines.