Overview
- Genoa beat Empoli 3-1 and will visit Atalanta, while Torino edged Pisa 1-0 to earn a trip to Roma in the next round.
- Venezia knocked out Hellas Verona on penalties 5-4 after a 0-0 draw in Verona to become the only second-division team still alive.
- Parma advanced past Spezia 4-3 on penalties after a 2-2 draw and will face defending cup holders Bologna.
- Como cruised past Sassuolo 3-0 at home and will meet Fiorentina in the round of 16.
- The completed last-16 slate in December also features Lazio vs AC Milan, Juventus vs Udinese, Napoli vs Cagliari, and Inter vs Venezia.