Overview
- First legs will be hosted by Flamengo and LDU Quito on 22 October, with second legs at Racing and Palmeiras on 29 October.
- Flamengo advanced by beating Estudiantes 4-2 in a penalty shootout after a 1-0 defeat in La Plata, highlighted by two saves from Agustín Rossi.
- Liga de Quito reached the last four with a 3-0 aggregate over São Paulo, capped by a 1-0 away win at Morumbi.
- Palmeiras eliminated River Plate, winning 3-1 at Allianz Parque after a 2-1 victory in Buenos Aires, with José López scoring twice late and Vítor Roque netting the equalizer.
- Racing booked its place by ousting Vélez Sarsfield 2-0 on aggregate under Gustavo Costas, securing a 1-0 win in each leg.