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Contaminated saline at Tamil Nadu dental clinic tied to eight deaths in neuromelioidosis outbreak

A May 2025 Lancet study identified Burkholderia pseudomallei ST1553 in reused saline, prompting officials to tighten infection controls.

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Overview

  • Ten patients contracted neuromelioidosis after irrigation with reused saline at a Vaniyambadi dental clinic, eight of whom died, yielding an 80% fatality rate.
  • The Lancet Regional Health Southeast Asia study linked the outbreak to bottles of saline opened with unsterile instruments and repeatedly reused during procedures.
  • Researchers determined that the bacteria likely spread directly along nerve pathways in the mouth, leading to rapid brainstem infections.
  • Following public outcry in May 2023, the clinic was disinfected and closed but scientists later isolated the pathogen from a preserved saline sample.
  • State public health authorities confirmed the findings and have implemented rigorous infection prevention and control measures across healthcare facilities.