Overview
- Kickoff is 4:25 p.m. ET on CBS with streaming on Paramount+ from Lucas Oil Stadium.
- Sportsbooks list Indianapolis around -14.5 with a total near 47.5, and the SportsLine model projects the Colts to cover with a 36–17 outcome.
- Indianapolis enters 6-1 behind an NFL-best 33.1 points per game and strong efficiency metrics across yards and points per drive.
- Tennessee will be without Pro Bowl lineman Jeffery Simmons and has placed cornerback L’Jarius Sneed on injured reserve, while edge rusher Arden Key is questionable.
- Rookie Cam Ward has a 57.6% completion rate with 5.8 yards per attempt and an NFL-high 30 sacks, coinciding with the Titans ranking last in scoring and total offense.