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With Kyler Murray Out, Colts Edge Cardinals 31–27 to Reach 5–1

Arizona turned to Jacoby Brissett as a mid-foot sprain clouds Murray’s short-term availability.

Overview

  • The Cardinals made Murray inactive pregame with a foot injury described by multiple reports as a mid-foot/Lisfranc-type sprain, and Jacoby Brissett was named the starter.
  • Brissett delivered a high-volume outing in his Arizona debut start, throwing for 320 yards with two touchdowns and one interception in the defeat.
  • Daniel Jones passed for two scores and ran for another, and Jonathan Taylor rushed for 123 yards with the late go-ahead touchdown as Indianapolis improved to 5-1.
  • NFL Network reported Murray’s sprain could cost him more than one week if aggravated, introducing uncertainty for Arizona entering Week 7.
  • Indianapolis turned to Michael Badgley at kicker after Spencer Shrader’s season-ending knee injury, and Arizona’s offense continues to cope with a thinned backfield with James Conner out for the season and Trey Benson on injured reserve.