Overview
- Arizona declared Kyler Murray inactive before kickoff, handing the start to veteran Jacoby Brissett, who went 27-of-44 for 320 yards with two touchdowns and one interception.
- Indianapolis improved to 5-1 as Daniel Jones passed for 212 yards with two scores and added a rushing touchdown, and Jonathan Taylor ran for 123 yards with the go-ahead 1-yard TD.
- The Cardinals’ last drive reached the Colts’ 9-yard line before a fourth-down incompletion ended the threat, sealing Arizona’s fourth straight one-score loss.
- The Colts dealt with unexpected pregame losses of QB Anthony Richardson (reported fractured orbital bone) and CB Charvarius Ward (concussion) and elevated RB Ameer Abdullah and CB Cameron Mitchell from the practice squad.
- Arizona elevated QB Kedon Slovis to the 53-man roster, and rookie WR Marvin Harrison Jr. exited with a concussion, adding to uncertainty as the team looks ahead to Week 7.