Colts and Texans Set for High-Stakes Season Opener

Indianapolis aims to end a 10-game Week 1 winless streak against Houston's rising stars.

Both teams feature second-year quarterbacks: C.J. Stroud for Houston and Anthony Richardson for Indianapolis.
Houston bolstered its offense with key additions like Joe Mixon and Stefon Diggs.
Indianapolis has struggled in recent openers, not winning since 2013.
Experts predict a high-scoring game with varied opinions on the outcome.
Key injuries include Houston's safety M.J. Stewart and Indy's kicker Matt Gay and receiver Josh Downs.