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Colossal Biosciences Unveils First Pack Encounters of Engineered Dire Wolves

Handlers are moving carefully toward full pack integration after successful play sessions in a secured research reserve.

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'Dire wolf' Khaleesi joins her brothers for the first time as the wolf pack begins to come together.

Overview

  • In mid-August, Colossal shared footage of staged introductions in which Khaleesi, the six-month-old female, met and played with older brothers Romulus and Remus, with handlers noting ears-up posture and controlled interactions.
  • The three canids live on a 2,000-plus-acre enclosed reserve equipped with zoo-grade fencing, live cameras, drone tracking and on-site veterinary facilities.
  • Colossal plans to engineer two to four more dire wolves over the next year using multiple cell lines to enhance genetic diversity rather than rely on natural breeding.
  • The company is collaborating with Grizzly Systems and Yellowstone’s Wolf Project to deploy audiovisual devices and AI software for passive, individual-level monitoring of pack behavior.
  • Scientists and ethicists continue to dispute whether these animals are true de-extinction or genetically modified gray wolves and question their long-term conservation and ethical implications.