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Colossal Biosciences' Genetic Advances Raise Conservation and Policy Concerns

The company’s creation of dire wolf proxies and cloned red wolves sparks debate over ecological risks, conservation priorities, and endangered species protections.

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This undated photo provided by Colossal Biosciences shows Romulus and Remus, both 3-months old and genetically engineered with similarities to the extinct dire wolf. (Colossal Biosciences via AP)
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Overview

  • Colossal Biosciences announced the creation of three genetically modified gray wolves with 20 edits to mimic the extinct dire wolf and four cloned red wolves from living canids.
  • Scientists warn that genetic technologies like cloning and gene editing may divert attention and funding from proven conservation methods such as habitat protection and invasive species control.
  • The red wolf, declared extinct in the wild in 1980, faces ongoing threats from habitat loss, hunting, and hybridization, with fewer than 20 individuals alive in captivity today.
  • Experts caution that cloning’s unknown long-term effects and ecological authenticity concerns make traditional breeding methods safer for red wolf recovery.
  • Interior Secretary Doug Burgum has cited Colossal’s genetic breakthroughs as justification to question the Endangered Species Act, intensifying the policy debate.