Overview

• Sanders underwent a four-hour procedure to remove blood clots this week, returned to practice, and said he will coach against the Cyclones.
• Iowa State dropped to No. 22 after a 38-30 loss at Cincinnati and enters Boulder at 5-1 (2-1 Big 12).
• The Big 12 availability report lists numerous Cyclones out or uncertain, including DB Jeremiah Cooper, WR Daniel Jackson, K/P Jace T. Gilbert, and others.
• Colorado is 2-4 (0-3 Big 12) after a 35-21 loss at TCU, with QB Kaidon Salter throwing for 217 yards and two touchdowns with three interceptions as the Buffs continue to lean on a resurgent run game.
• Kickoff is Saturday at 1:30 p.m. MT (3:30 p.m. ET) at Folsom Field on ESPN.