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Colorado Dentist’s Murder Trial Opens with Poisoning and Murder-for-Hire Allegations

Opening statements detailed prosecutors’ allegation that James Craig poisoned his wife’s shakes with cyanide, arsenic and tetrahydrozoline before plotting to bribe inmates to kill the lead investigator

FILE - This undated booking photo provided by the Aurora, Colorado Police Department shows James Craig.
James Craig talks with his family from his seat before opening arguments in his murder trial, as he is accused of killing his wife, at the Arapahoe District Court, Tuesday, July 15, 2025, in Centennial, Colo. (Stephen Swofford via Denver Gazette, Pool)
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FILE - Law enforcement personnel provide security for a court appearance at the Arapahoe County Courthouse, July 23, 2012, in Centennial, Colo. (AP Photo/Alex Brandon, File)

Overview

  • Fifteen jurors were selected and opening statements began on July 15 in Arapahoe County District Court, marking the start of a trial expected to last several weeks.
  • Prosecutors allege Craig laced his wife’s protein shakes with arsenic, potassium cyanide and tetrahydrozoline and later injected her with poison during her final hospital stay.
  • Court records show Craig conducted online searches on disguising a murder as a heart attack and the detectability of arsenic in autopsies, which prosecutors say demonstrates premeditation.
  • Investigators say Craig offered at least $20,000 to jailhouse informants to kill the lead investigator and recruit false witnesses to back a suicide theory.
  • The defense has challenged the credibility of jailhouse informants, highlighted the absence of poison residue in tested containers and accused investigators of bias.