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College Top 10 Turmoil Meets Data-Driven NFL Week 6 Picks

Fresh projections spotlight edges that diverge from several betting lines.

Overview

  • After upsets dropped Penn State and Texas from the Top 10, Ohio State sits at No. 1 in Chris Fallica’s ranking, with the Buckeyes’ defense credited with allowing just two touchdowns all season.
  • SportsLine’s 10,000-simulation model backs Dallas to cover -3.5 at Carolina in nearly 60% of simulations and has Tampa Bay covering -3 vs. San Francisco in a majority of runs, with the total also leaning Over.
  • The model promotes a roughly 25-1, five-leg parlay and is especially high on Buffalo -4.5 at Atlanta, projecting the Bills to win nearly 80% of simulations and cover well over 70%.
  • ESPN’s Matchup Predictor assigns notable win probabilities: Eagles 74.8% over the Giants, Broncos 71% over the Jets in London, Packers 80.1% over the Bengals, Buccaneers 51.1% over the 49ers, and Chiefs 53.4% over the Lions.
  • Analysts flag Detroit at Kansas City as a prime upset candidate, with FOX Sports recommending Lions +2.5 and CBS Sports listing Lions–Chiefs and 49ers–Buccaneers among favorites most at risk.