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Coiled Optic Nerves Explain Chameleons’ Independent Eye Movements

MicroCT imaging in Scientific Reports resolved a centuries-old anatomical puzzle by revealing telephone-cord-like loops that provide slack for extreme eye rotation.

Overview

  • Using contrast-enhanced microCT and 3D modeling, researchers identified telephone-cord-like loops in the optic nerves of multiple, distantly related chameleon species.
  • The coils extend each nerve to as much as roughly three times the straight brain-to-eye distance, supplying slack that enables wide, independent scanning before precise binocular targeting of prey.
  • Embryonic imaging of veiled chameleons showed the nerves start straight and twist into loops by hatching, indicating the structure forms late in development.
  • Comparative scans of more than 30 reptiles, including three chameleons from different lineages, found the coiled design in chameleons but not in other lizards or snakes examined.
  • Non-destructive imaging corrected misreadings from historical dissections, and the authors propose the coils may have evolved to compensate for chameleons’ stiff necks, a premise that awaits further testing.