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Cocoa Flavanols Shield Arteries From Two Hours of Sitting in Young Men, Study Finds

The peer-reviewed study links flavanol intake to preserved flow-mediated dilation independent of fitness level.

Overview

  • University of Birmingham researchers reported in the Journal of Physiology that a single high-flavanol cocoa drink prevented sitting-related declines in vascular function.
  • Forty healthy men consumed either a high-flavanol beverage (695 mg total flavanols) or a low-flavanol control (5.6 mg) before two hours of uninterrupted sitting.
  • High-flavanol intake preserved flow-mediated dilation in arm and leg arteries, whereas the low-flavanol groups showed reduced FMD, higher diastolic blood pressure, lower blood flow, and decreased muscle oxygenation.
  • Authors cite nitric oxide–mediated vasodilation as the likely mechanism for the short-term protection observed after flavanol consumption.
  • The trial included only men and was acute and laboratory-based, with researchers calling for studies in women and longer-term outcomes; flavanols are also found in tea, berries, apples, and some nuts.