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CMS Sets 2027 Medicare Prices for 15 High-Cost Drugs, Including Ozempic and Wegovy

The enforceable Inflation Reduction Act negotiations set 2027 maximum fair prices for high‑spend Part D medicines, with CMS projecting $12 billion in savings.

Overview

  • The new prices cover 15 Part D drugs across diabetes, cancer, respiratory disease and other conditions, and they take effect on January 1, 2027.
  • CMS estimates roughly $12 billion in program savings and $685 million in enrollee out‑of‑pocket savings in 2027, though some reports cite an $8.5 billion figure based on a different comparison.
  • Semaglutide products Ozempic and Rybelsus were set at about $274 for a 30‑day supply and higher‑dose Wegovy at $385, which is above a separate voluntary $245 deal announced for GLP‑1s outside the IRA process.
  • The 15 medicines accounted for about $42.5 billion in gross Part D spending in 2024 and were used by approximately 5.3 million enrollees.
  • Manufacturers face penalties or withdrawal from Medicare if they reject the negotiated prices, and industry legal challenges to the program have so far been unsuccessful.