Overview
- Kickoff is set for 8:15 p.m. ET at NRG Stadium, streamed nationally on Prime Video.
- Davis Mills is expected to start for Houston with C.J. Stroud still in concussion protocol and ruled out for Thursday.
- Buffalo’s Monday walkthrough listed four DNPs — Dalton Kincaid, Mecole Hardman, Curtis Samuel and Phidarian Mathis — with multiple others limited, and Khalil Shakir later missing time for personal reasons.
- Houston enters with the NFL’s top-ranked defense, leading the league in yards allowed per game (258.1) and points allowed per game (16.3).
- Sportsbooks opened with Buffalo favored by about 5.5 points and a total of 43.5, with playoff positioning in focus for both teams.