Overview
- Applegate said on her MeSsy podcast that clinicians now believe her 2021 MS diagnosis may have been wrong and that she remains unwell, a disclosure first reported in coverage on Oct. 20 that reset her care and public profile.
- Her care team has paused certain infusions and ordered further cell and test reviews as doctors re-examine the original studies and seek an alternative diagnosis.
- Megyn Kelly criticized Applegate on The Megyn Kelly Show by calling the situation a “wild goose chase” and suggesting Applegate sought to be “the face of MS,” comments that were widely quoted in coverage.
- Co-hosts on ABC’s The View and commentators including Ana Navarro sharply condemned Kelly’s remarks as cruel, defending Applegate’s reported ongoing pain and visible disability and citing a Cedars–Sinai neurologist’s podcast explanation of why MS can be misdiagnosed.
- The case highlights how MS is diagnosed without a single definitive test, how a revised diagnosis can unsettle a patient’s identity and advocacy work, and what to watch next as clinicians complete their review and any formal findings are announced.