Overview
- Applegate, who said on October 20 that doctors concluded she does not have the multiple sclerosis diagnosis she received in 2021, has returned to medical testing to seek another explanation.
- Her medical team is performing sequential tests and specialist referrals to check for rheumatoid arthritis, lupus, Lyme disease and similar disorders that can produce MS‑like symptoms.
- Clinicians have paused or rechecked some prior therapies and are re‑reviewing earlier scans and lab work as part of the new diagnostic process.
- Despite the reversal, Applegate continues to experience severe mobility and pain problems—she still uses a wheelchair for some appointments and has not seen improvement in daily function.
- The case highlights limits in MS diagnosis, notes that newer evaluation technology contributed to the correction, and could prompt broader re‑examinations of inconclusive or long‑standing MS diagnoses.