Overview
- Applegate disclosed the update on her MeSsy podcast on Tuesday, saying doctors using new technology told her, “Congratulations, you don’t have MS,” but that she feels “back at square one.”
- She reports that her physical condition has not improved and in some ways has worsened, and that she still needs mobility aids for doctor visits and cannot walk short distances.
- Applegate described a severe emotional and practical toll from the earlier diagnosis, saying it led to depression, lost work and a changed public role as an advocate for the MS community.
- Dr. Marwa Kaisey, a Cedars‑Sinai neurologist on the podcast, explained that MS has no single definitive test and that research suggests nearly one in five people told they have MS may later learn they were misdiagnosed.
- Applegate’s medical team will now run further testing to find the true cause of her symptoms, a search that could affect past treatment decisions, future care and the public narrative she built while living under the MS label.