Overview

• During the July 30 episode of “Let’s Talk Off Camera With Kelly Ripa,” Applegate revealed Sadie told her, “I missed who you were before you got sick.”
• Applegate, who disclosed her MS diagnosis in 2021, said her daughter’s support is the driving force that gets her out of bed each day.
• She described the comment as a “knife to the heart,” reflecting her own grief over the losses imposed by multiple sclerosis.
• Applegate remains candid about her daily battles and family dynamics on the “MesSy” podcast she co-hosts with fellow MS survivor Jamie-Lynn Sigler.
• Her openness aims to raise awareness about the emotional toll and practical challenges of living with multiple sclerosis.