Overview
- Applegate revealed on her MeSsy podcast on Tuesday that a clinician told her she does not have multiple sclerosis after follow‑up testing and review.
- She said the change did not improve her health and that her symptoms have persisted or in some ways worsened, leaving her reliant on mobility aids and in ongoing physical therapy.
- Applegate described that clinicians paused an infusion to watch her B cells and used updated MRI analysis, steps that prompted specialists to reexamine the original 2021 diagnosis.
- Her medical team will begin a coordinated investigation next week to identify alternative causes for the neurologic symptoms that began before 2021 and to review prior tests and treatments.
- Doctors on the show explained there is no single diagnostic test for MS, that misdiagnosis is relatively common, and that such errors can lead to years of unnecessary therapies and serious personal and professional consequences.