Overview
- Applegate announced that doctors told her she does not have multiple sclerosis and that she is restarting testing to find another cause for her persistent pain and mobility loss.
- She raised the possibility that saline implants placed after her 2008 double mastectomy could be leaking and producing MS‑like symptoms, and said she will investigate that theory with her doctors.
- Applegate described worsening joint pain and loss of use in her right shoulder that have continued even after the MS diagnosis was rescinded.
- Her medical team is running stepwise evaluations for conditions that can mimic MS, including rheumatoid arthritis, lupus and Lyme disease, and is rechecking earlier test results.
- Medical experts and regulators note that observational studies and patient reports show links between implants and fatigue, joint pain or cognitive complaints but that well‑designed studies and the FDA have not established a causal relationship.