Christina Applegate Opens Up About Severe Depression Linked to MS

The actress shares her ongoing mental health struggles and the impact of her multiple sclerosis diagnosis.

Applegate describes experiencing a deep, 'fatalistic' depression since her MS diagnosis in 2021.
She admits to avoiding therapy due to fear of overwhelming emotions.
Co-host Jamie-Lynn Sigler encourages her to confront and accept her feelings.
Applegate highlights the physical challenges and pain associated with MS.
She reveals the therapeutic value of her conversations with Sigler on their podcast.