Christian McCaffrey Set for Season Debut Against Buccaneers

49ers look to revitalize their offense with McCaffrey's return from injury in crucial matchup.

Christian McCaffrey is expected to make his season debut after recovering from Achilles tendinitis, providing a needed boost to the 49ers' struggling red zone offense.
The 49ers have struggled without McCaffrey, ranking 27th in red zone efficiency, but his return could improve their touchdown production.
Rookie running back Isaac Guerendo has stepped up in McCaffrey's absence, showing promise with strong performances, including a standout game against the Cowboys.
The Buccaneers, dealing with their own injuries, face a potentially challenging game with a depleted defense that played 85 snaps in their last outing.
Baker Mayfield, despite a toe injury, remains a key threat for the Buccaneers, leading the NFL in touchdown passes this season.