Overview
- McCaffrey logged 21 carries for 117 yards and caught six passes for 29 yards with two receiving touchdowns against Indianapolis.
- The performance pushed him to 1,039 rushing yards on the year and kept him 151 receiving yards shy of a 1,000–1,000 campaign.
- He tied Marshall Faulk for the most career receiving touchdowns by a running back in the Super Bowl era with 36.
- San Francisco improved to 11–4 with its fifth straight victory, overpowering the Colts 48–27 on Monday night.
- Brock Purdy completed 25 of 34 passes for 295 yards and five touchdowns, while the 49ers now host the Bears and Seahawks to close the regular season.