Overview

• The 49ers’ official inactives confirmed McCaffrey will play, with seven players out including rookie running back Jordan James.
• McCaffrey was listed as questionable after practicing fully Wednesday, going limited Thursday with a calf issue, and not practicing Friday.
• Team moves reinforced optimism as no running backs were elevated from the practice squad, while WR Russell Gage and LB Curtis Robinson were promoted.
• Recent trade acquisition Brian Robinson Jr., along with rookie Isaac Guerendo, provides insurance if the team tapers McCaffrey’s touches.
• The Seahawks elevated defensive tackle Quinton Bohanna and cornerback Shaquill Griffin from the practice squad for Week 1.