Overview

• A genetically modified pig liver was transplanted into a brain-dead human in China, functioning effectively for 10 days.
• The pig liver demonstrated stable blood flow, bile production, and immune compatibility, though its bile and albumin output were lower than human livers.
• The transplant was conducted as an auxiliary procedure, supporting the patient's existing liver, and was terminated at the family's request.
• Researchers aim to use such transplants as 'bridge organs' for patients awaiting human liver donors, with future trials planned for living patients.
• The study highlights the potential of xenotransplantation to alleviate organ shortages but underscores the need for further research into the liver's complex functions.