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Chinese Doctors Achieve Milestone in Pig Organ Transplants

A genetically modified pig kidney functions successfully in a human patient, while a pig liver transplant shows promise as a bridge therapy for organ failure.

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Overview

  • Chinese researchers successfully transplanted a genetically modified pig kidney into a 69-year-old woman, marking her as the third person globally to live with such an organ.
  • Three weeks post-operation, the kidney continues to function well, with the patient reportedly in excellent health under close monitoring.
  • The team also conducted the world's first transplant of a genetically modified pig liver into a brain-dead human, with the organ functioning for 10 days and producing bile without early rejection signs.
  • Six genetic modifications were made to the donor pigs to reduce rejection risks, showcasing advancements in genetic engineering for xenotransplantation.
  • These breakthroughs highlight the potential of pig organs as solutions to the global organ shortage, though routine clinical use remains a distant goal due to unresolved challenges.