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Childhood Inflammation Linked to Higher Risk of Mental Health Issues

University of Birmingham study finds early inflammation significantly increases chances of psychosis and depression in adulthood.

  • Children with elevated inflammation markers at age 9 are five times more likely to develop psychosis or schizophrenia.
  • The study used data from the Avon Longitudinal Study of Parents and Children, tracking participants from birth.
  • Persistently raised inflammation is also linked to higher risks of depression and cardiometabolic diseases like insulin resistance.
  • Researchers highlight the need for further studies to determine if inflammation is a causal factor or an indicator.
  • Potential early interventions and new treatment targets could emerge from understanding the role of inflammation in mental health.
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