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Chiefs–Chargers Open Week 1 in São Paulo on YouTube’s First Live NFL Game

The league is leveraging a Brazil opener to showcase its expanding international slate through YouTube's first live NFL broadcast.

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Can Justin Herbert and the Los Angeles Chargers beat the Kansas City Chiefs on Sept. 5? NFL Week 1 picks, predictions and odds preview the game Friday in Brazil.
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Overview

  • Kickoff is Friday, Sept. 5 at 8 p.m. ET at Arena Corinthians, with exclusive global streaming on YouTube.
  • The matchup headlines a record seven international regular-season games in 2025, including first-time stops in Berlin, Dublin and Madrid.
  • Betting markets lean Kansas City, with the Chiefs favored by 3 points and ESPN’s model giving them about a 57% win chance.
  • Chargers coach Jim Harbaugh called it a “world stage,” as Patrick Mahomes drew loud greetings from Brazilian fans after the teams arrived.
  • After complaints about last year’s turf and travel challenges, officials say field conditions have been addressed, and the show will include a halftime performance by Karol G.