Chiefs' Lead Running Back Isiah Pacheco Ruled Out Due to Injury

Clyde Edwards-Helaire Expected to Step Up in Game Against Buffalo Bills

Kansas City Chiefs' lead running back Isiah Pacheco is ruled out due to a shoulder injury.
Clyde Edwards-Helaire is expected to step up and take a central role in the upcoming game against the Buffalo Bills.
Edwards-Helaire, a 2020 first-round pick, lost his job as the regular featured back to Pacheco last season.
Other running backs available for the Chiefs are Jerick McKinnon and Deneric Prince.
This could be one of Edwards-Helaire's last chances to return their investment in him as a draft pick, as the Chiefs declined to exercise the fifth-year option on his contract.