Overview

• Kickoff is 8:15 p.m. ET at EverBank Stadium in Jacksonville on ABC and ESPN, with a Manningcast on ESPN2.
• Betting lines sit around Chiefs -3.5 with a 45.5-point total and moneyline prices near Kansas City -200 and Jacksonville in the mid +160s, depending on the sportsbook.
• Multiple projection models lean to the Under near 45 points and slightly favor Kansas City to cover, while expert picks are mixed across outlets.
• Kansas City is 2-2 after a 37-20 win over the Ravens featuring four Patrick Mahomes touchdown passes; Jacksonville is 3-1 following a 26-21 road win over the 49ers.
• The Chiefs have won eight straight against the Jaguars, but Jacksonville leads the NFL with 13 takeaways and a +9 turnover margin, with Travis Etienne pacing a run-first attack and Kansas City boosted by Xavier Worthy’s return as Rashee Rice remains suspended.