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ChatGPT-Fueled Salt Swap Leads to Bromide Toxicity and Prompts AI Safeguards

Recovery after three weeks in hospital underscores risks of unverified AI health guidance, with OpenAI moving to tighten safeguards

Overview

  • A 60-year-old man replaced dietary sodium chloride with sodium bromide for three months after consulting ChatGPT, sourcing the compound online based on halide swap suggestions
  • He developed paranoia, auditory and visual hallucinations, and extreme thirst, resulting in emergency admission and an involuntary psychiatric hold
  • Physicians ran broad laboratory tests that revealed multiple micronutrient deficiencies and elevated bromide levels, diagnosing acute bromism and treating him with fluids, electrolyte repletion, and antipsychotics
  • The case was published Aug. 5 in Annals of Internal Medicine Clinical Cases, reviving awareness of bromism, a toxicity syndrome once responsible for up to 10 percent of early 20th-century psychiatric admissions
  • Report authors and medical bodies warned that large language models can generate dangerous medical inaccuracies, prompting OpenAI to reiterate usage terms and plan enhanced health-related safety measures