Overview
- Harris collapsed without contact after planting his left leg with about five minutes left in the second quarter at SoFi Stadium.
- He was helped off, carted to the locker room and downgraded from questionable with an ankle issue to out for the game.
- Coach Jim Harbaugh said preliminary evaluation indicated an Achilles injury and noted that Harris underwent postgame imaging to assess severity.
- Multiple outlets report the injury is likely season-ending, and Hampton stepped in with 19 carries for 70 yards and a touchdown plus six receptions for 59 yards.
- Before exiting, Harris had six carries for 28 yards; the veteran had never missed an NFL game and entered 2025 after a July 4 eye injury that cost him training camp.