Overview

• Los Angeles (3-2) visits Miami (1-4) on Sunday at 1 p.m. EDT on CBS, with sportsbooks listing the Chargers by roughly 3.5 to 4.5 points.
• Miami enters without Tyreek Hill for the season and with a thinned cornerback room after multiple IR placements, straining a defense already under pressure.
• The Chargers placed rookie RB Omarion Hampton on injured reserve and are also without Najee Harris, leaving Hassan Haskins and Kimani Vidal to handle carries.
• Protection is a central concern for Los Angeles with injuries on the offensive line and 17 sacks allowed through five games, including uncertainty for tackles Joe Alt and Rashawn Slater’s replacement plan.
• Los Angeles added pass rusher Odafe Oweh this week in a trade and he is expected to play, while a key on-field storyline is whether the Chargers can exploit Miami’s NFL-worst run defense (about 174 rushing yards allowed per game).