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CDC Shifts Hepatitis B Newborn Vaccination to Shared Decision-Making

The change moves the birth dose to shared decision-making for infants of hepatitis B–negative mothers, with high-risk newborns still vaccinated within 12 hours.

Overview

  • The CDC on Dec. 16 aligned with ACIP to end routine hepatitis B shots at birth for infants of mothers who test negative, advising parent‑clinician discussion instead.
  • Babies born to mothers who are positive for hepatitis B or whose status is unknown should still receive vaccine plus hepatitis B immune globulin within 12 hours of birth.
  • For infants who skip the birth dose, the CDC suggests beginning the vaccine series no earlier than two months of age.
  • Several hospital systems and state health departments say they will continue offering the birth dose, and the American Academy of Pediatrics condemned the federal change as likely to increase infections.
  • The CDC is reviewing ACIP’s separate proposal for post‑dose serology testing, and coverage through insurers and the Vaccines for Children program remains in place.