Overview

• Locally acquired human infections are confirmed in eight states: Texas, California, Arizona, Louisiana, Tennessee, Missouri, Mississippi and Arkansas.
• The literature review documents infected triatomine vectors in 32 states, with authors warning that current non‑endemic labeling sustains low awareness and underreporting.
• Canine infections are reported in 23 states as well as Washington, D.C., and the U.S. Virgin Islands, with wildlife reservoirs identified in at least 17 states.
• Most states do not require case reporting, and estimates suggest roughly 280,000 to 300,000 people in the U.S. may be infected, many without a diagnosis.
• Transmission can also occur via contaminated food, blood products, organ transplants and from mother to baby, and early antiparasitic treatment is most effective.