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CDC Confirms Transplant-Linked Rabies Death, Urges Tighter Donor Risk Checks

Health officials now recommend transplant teams consult public health if a donor has recent animal exposure or acute neurologic illness.

Overview

  • The CDC linked a Michigan kidney recipient’s fatal rabies to an Idaho donor after archived kidney tissue from the donor tested positive for rabies virus RNA.
  • The donor had been scratched by a skunk weeks before dying, and laboratory results indicated a bat-associated strain consistent with a bat–skunk–donor–recipient transmission chain.
  • Three people who received corneal grafts from the same donor had the grafts removed and received post-exposure prophylaxis, and one cornea tested positive for rabies.
  • Public health officials reviewed 357 potential contacts tied to the donor and recipient and recommended post-exposure prophylaxis for 46 individuals.
  • Transplant-transmitted rabies is extraordinarily rare in the U.S., with only four donor-associated events documented since 1978, and the donor’s heart and lungs were used only for training, not transplantation.