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CDC Confirms Fatal Rabies Transmission Through Donor Kidney in Rare U.S. Transplant Case

The report traces the infection to bat-linked rabies in the donor’s kidney tissue, exposing limits in current donor screening.

Overview

  • A Michigan patient died weeks after a December 2024 kidney transplant, with CDC testing linking his illness to rabies acquired from the donor organ.
  • Archived biopsy material from the Idaho donor’s kidney was positive for rabies virus RNA while stored serum tested negative, indicating diagnostic blind spots.
  • Genetic analysis was consistent with the silver-haired bat variant, supporting a likely chain of transmission from bat to skunk to donor to recipient.
  • Three corneal graft recipients had their transplants removed, received post-exposure prophylaxis, and remained asymptomatic, with one cornea testing positive.
  • Public health teams assessed 357 potential contacts and recommended prophylaxis for 46 people, as CDC urges consultation when donors report recent animal exposures.