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CCMB Scientists Report 'Programmed Cell Revival' That Restores Cells and Speeds Regeneration

The peer-reviewed study describes a conserved revival program reactivating growth pathways in dying cells.

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Overview

  • Led by Dr Santosh Chauhan in Hyderabad, the work from the CSIR-Centre for Cellular and Molecular Biology is published in the EMBO Journal.
  • Experiments showed the phenomenon sped up healing of skin wounds and repaired corneal burns in mice.
  • The team also observed stimulated tail regrowth in frog tadpoles, improved nerve repair in worms, and increased blood stem-cell production in fruit flies.
  • Researchers say the process mimics developmental programs and reactivates metabolic and immune pathways to restore full cellular function.
  • They warn that cancer drug screens may misread cells as dead even if they later revive with stem-like traits, and they have filed Indian and international patents.